Dalian Institute of Chemical Industry developed the first short-wavelength chiral Raman spectrometer

Recently, the "Development of Short-wavelength Chiral Raman Spectrometer for Electric-field and Magnetic-Field-modulated Short-wavelength Chiral Raman Spectrometer" by Academician Li Can and Research Fellow Feng Yuanchi has passed the national acceptance test. The related progress was also published in Applied Spectroscopy. This marks the successful development of the first 457nm laser as the excitation source of the short wavelength chiral Raman spectrometer.

Chiral Raman spectroscopy is a new spectroscopic method for the characterization of chiral molecules. This method does not require crystallization of the sample. It can directly identify the absolute configuration of the chiral sample in the solution phase and is therefore subject to academic and industrial research. The height of attention. However, the chiral Raman spectroscopy signal is 3 to 7 orders of magnitude weaker than the conventional spectrum, and the experiment is difficult. On the basis of years of research, the research team of Dalian Institute of Technology has proposed the development ideas of short-wavelength chiral Raman spectroscopy instruments, optimised the selection of a 457 nm laser suitable for chiral Raman spectroscopy as a light source, and cooperated with relevant spectroscopic instruments companies at home and abroad. The first short wavelength chiral Raman spectrometer was successfully developed.

The project achievements were recently approved by the National Natural Science Foundation of China for the research and development of a major national scientific research instrument and equipment project. At the 19th National Conference on Light Scattering recently held, a 457 nm short-wavelength chiral Raman spectrum seminar was also held.

It is understood that the spectrometer has achieved an order of more than 2 million yuan, and it is expected to play an important role in the identification of chiral molecules, synthesis and identification of new drugs, asymmetric catalysis, and research of biological macromolecules.


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